Muktha entered malayalam film industry through the film Ottananayam. It was a small role for her but, the 2005 movie Achanurangatha Veedu, was a superhit and Muktha received appreciations for her performance too. In 2006, Muktha acted in a Telugu film Photo. She did the role as Bhanu in that movie and also accepted her screen name as Bhanu there after. In 2007, Vishal starrer Thamirabharani got her the nomination for Vijay Awards for Best New comer. Following the success of the film, she starred in a number of films such as Goal, Nasrani, Hailesa, Kancheepurathe Kalyanam, Avan, Khilafath, Chaverpada, Shivapuram, Ee Thirakkinidayil , Manthrikan, The Filmstar, Holidays, Room No. 9B, Ginger in malayalam and films like Rasigar Manram, Azhagar Malai, Sattapadi Kutram, Ponnar Shankar, Pudhumughangal Thevai, Moondru Per Moondru Kadhal, Desingu Raja, Vaaimai, Sagunthalaavin Kathalan etc in Tamil too. Among these, characters portrayed in Nasrani, Puthumugangal Thevai and Moondru Per Moondru Kathal were highly appreciated by critic and movie fans.